| English Premiership Results | ||||||
| August 13 | 2021 | 20:00 | Brentford | 2 | 0 | Arsenal |
| August 14 | 2021 | 12:30 | Manchester U. | 5 | 1 | Leeds United |
| August 14 | 2021 | 15:00 | Burnley | 1 | 2 | Brighton |
| August 14 | 2021 | 15:00 | Chelsea | 3 | 0 | Crystal Palace |
| August 14 | 2021 | 15:00 | Everton | 3 | 1 | Southampton |
| August 14 | 2021 | 15:00 | Leicester | 1 | 0 | Wolves |
| August 14 | 2021 | 15:00 | Watford | 3 | 2 | Aston Villa |
| August 14 | 2021 | 17:30 | Norwich City | 0 | 3 | Liverpool |
| August 15 | 2021 | 14:00 | Newcastle | 2 | 4 | West Ham U. |
| August 15 | 2021 | 16:30 | Tottenham H. | 1 | 0 | Manchester C. |
| August 21 | 2021 | 12:30 | Liverpool | 2 | 0 | Burnley |
| August 21 | 2021 | 15:00 | Aston Villa | 2 | 0 | Newcastle |
| August 21 | 2021 | 15:00 | Crystal Palace | 0 | 0 | Brentford |
| August 21 | 2021 | 15:00 | Leeds United | 2 | 2 | Everton |
| August 21 | 2021 | 15:00 | Manchester C. | 5 | 0 | Norwich City |
| August 21 | 2021 | 17:30 | Brighton | 2 | 0 | Watford |
| August 22 | 2021 | 14:00 | Southampton | 1 | 1 | Manchester U. |
| August 22 | 2021 | 14:00 | Wolves | 0 | 1 | Tottenham H. |
| August 22 | 2021 | 16:30 | Arsenal | 0 | 2 | Chelsea |
| August 23 | 2021 | 20:00 | West Ham U. | 4 | 1 | Leicester |
| August 28 | 2021 | 12:30 | Manchester C. | 5 | 0 | Arsenal |
| August 28 | 2021 | 15:00 | Aston Villa | 1 | 1 | Brentford |
| August 28 | 2021 | 15:00 | Brighton | 0 | 2 | Everton |
| August 28 | 2021 | 15:00 | Newcastle | 2 | 2 | Southampton |
| August 28 | 2021 | 15:00 | Norwich City | 1 | 2 | Leicester |
| August 28 | 2021 | 15:00 | West Ham U. | 2 | 2 | Crystal Palace |
| August 28 | 2021 | 17:30 | Liverpool | 1 | 1 | Chelsea |
| August 29 | 2021 | 14:00 | Burnley | 1 | 1 | Leeds United |
| August 29 | 2021 | 14:00 | Tottenham H. | 1 | 0 | Watford |
| August 29 | 2021 | 16:30 | Wolves | 0 | 1 | Manchester U. |
| September 11 | 2021 | 12:30 | Crystal Palace | 3 | 0 | Tottenham H. |
| September 11 | 2021 | 15:00 | Arsenal | 1 | 0 | Norwich City |
| September 11 | 2021 | 15:00 | Brentford | 0 | 1 | Brighton |
| September 11 | 2021 | 15:00 | Leicester | 0 | 1 | Manchester C. |
| September 11 | 2021 | 15:00 | Manchester U. | 4 | 1 | Newcastle |
| September 11 | 2021 | 15:00 | Southampton | 0 | 0 | West Ham U. |
| September 11 | 2021 | 15:00 | Watford | 0 | 2 | Wolves |
| September 11 | 2021 | 17:30 | Chelsea | 3 | 0 | Aston Villa |
| September 12 | 2021 | 16:30 | Leeds United | 0 | 3 | Liverpool |
| September 13 | 2021 | 20:00 | Everton | 3 | 1 | Burnley |
| September 17 | 2021 | 20:00 | Newcastle | 1 | 1 | Leeds United |
| September 18 | 2021 | 12:30 | Wolves | 0 | 2 | Brentford |
| September 18 | 2021 | 15:00 | Burnley | 0 | 1 | Arsenal |
| September 18 | 2021 | 15:00 | Liverpool | 3 | 0 | Crystal Palace |
| September 18 | 2021 | 15:00 | Manchester C. | 0 | 0 | Southampton |
| September 18 | 2021 | 15:00 | Norwich City | 1 | 3 | Watford |
| September 18 | 2021 | 17:30 | Aston Villa | 3 | 0 | Everton |
| September 19 | 2021 | 14:00 | Brighton | 2 | 1 | Leicester |
| September 19 | 2021 | 14:00 | West Ham U. | 1 | 2 | Manchester U. |
| September 19 | 2021 | 16:30 | Tottenham H. | 0 | 3 | Chelsea |
| September 25 | 2021 | 12:30 | Chelsea | 0 | 1 | Manchester C. |
| September 25 | 2021 | 15:00 | Manchester U. | 0 | 1 | Aston Villa |
| September 25 | 2021 | 15:00 | Everton | 2 | 0 | Norwich City |
| September 25 | 2021 | 15:00 | Leeds United | 1 | 2 | West Ham U. |
| September 25 | 2021 | 15:00 | Leicester | 2 | 2 | Burnley |
| September 25 | 2021 | 15:00 | Watford | 1 | 1 | Newcastle |
| September 25 | 2021 | 17:30 | Brentford | 3 | 3 | Liverpool |
| September 26 | 2021 | 14:00 | Southampton | 0 | 1 | Wolves |
| September 26 | 2021 | 16:30 | Arsenal | 3 | 1 | Tottenham H. |
| September 27 | 2021 | 20:00 | Crystal Palace | 1 | 1 | Brighton |
| October 2 | 2021 | 12:30 | Manchester U. | 1 | 1 | Everton |
| October 2 | 2021 | 15:00 | Burnley | 0 | 0 | Norwich City |
| October 2 | 2021 | 15:00 | Chelsea | 3 | 1 | Southampton |
| October 2 | 2021 | 15:00 | Leeds United | 1 | 0 | Watford |
| October 2 | 2021 | 15:00 | Wolves | 2 | 1 | Newcastle |
| October 2 | 2021 | 17:30 | Brighton | 0 | 0 | Arsenal |
| October 3 | 2021 | 14:00 | Crystal Palace | 2 | 2 | Leicester |
| October 3 | 2021 | 14:00 | Tottenham H. | 2 | 1 | Aston Villa |
| October 3 | 2021 | 14:00 | West Ham U. | 1 | 2 | Brentford |
| October 3 | 2021 | 16:30 | Liverpool | 2 | 2 | Manchester C. |
| October 16 | 2021 | 12:30 | Watford | 0 | 5 | Liverpool |
| October 16 | 2021 | 15:00 | Aston Villa | 2 | 3 | Wolves |
| October 16 | 2021 | 15:00 | Leicester | 4 | 2 | Manchester U. |
| October 16 | 2021 | 15:00 | Manchester C. | 2 | 0 | Burnley |
| October 16 | 2021 | 15:00 | Norwich City | 0 | 0 | Brighton |
| October 16 | 2021 | 15:00 | Southampton | 1 | 0 | Leeds United |
| October 16 | 2021 | 17:30 | Brentford | 0 | 1 | Chelsea |
| October 17 | 2021 | 14:00 | Everton | 0 | 1 | West Ham U. |
| October 17 | 2021 | 16:30 | Newcastle | 2 | 3 | Tottenham H. |
| October 18 | 2021 | 20:00 | Arsenal | 2 | 2 | Crystal Palace |
| October 22 | 2021 | 20:00 | Arsenal | 3 | 1 | Aston Villa |
| October 23 | 2021 | 12:30 | Chelsea | 7 | 0 | Norwich City |
| October 23 | 2021 | 15:00 | Crystal Palace | 1 | 1 | Newcastle |
| October 23 | 2021 | 15:00 | Everton | 2 | 5 | Watford |
| October 23 | 2021 | 15:00 | Leeds United | 1 | 1 | Wolves |
| October 23 | 2021 | 15:00 | Southampton | 2 | 2 | Burnley |
| October 23 | 2021 | 17:30 | Brighton | 1 | 4 | Manchester C. |
| October 24 | 2021 | 14:00 | Brentford | 1 | 2 | Leicester |
| October 24 | 2021 | 14:00 | West Ham U. | 1 | 0 | Tottenham H. |
| October 24 | 2021 | 16:30 | Manchester U. | 0 | 5 | Liverpool |
| October 30 | 2021 | 12:30 | Leicester | 0 | 2 | Arsenal |
| October 30 | 2021 | 15:00 | Burnley | 3 | 1 | Brentford |
| October 30 | 2021 | 15:00 | Liverpool | 2 | 2 | Brighton |
| October 30 | 2021 | 15:00 | Manchester C. | 0 | 2 | Crystal Palace |
| October 30 | 2021 | 15:00 | Newcastle | 0 | 3 | Chelsea |
| October 30 | 2021 | 15:00 | Watford | 0 | 1 | Southampton |
| October 30 | 2021 | 17:30 | Tottenham H. | 0 | 3 | Manchester U. |
| October 31 | 2021 | 14:00 | Norwich City | 1 | 2 | Leeds United |
| October 31 | 2021 | 16:30 | Aston Villa | 1 | 4 | West Ham U. |
| November 1 | 2021 | 20:00 | Wolves | 2 | 1 | Everton |
| November 5 | 2021 | 20:00 | Southampton | 1 | 0 | Aston Villa |
| November 6 | 2021 | 12:30 | Manchester U. | 0 | 2 | Manchester C. |
| November 6 | 2021 | 15:00 | Brentford | 1 | 2 | Norwich City |
| November 6 | 2021 | 15:00 | Chelsea | 1 | 1 | Burnley |
| November 6 | 2021 | 15:00 | Crystal Palace | 2 | 0 | Wolves |
| November 6 | 2021 | 17:30 | Brighton | 1 | 1 | Newcastle |
| November 7 | 2021 | 14:00 | Arsenal | 1 | 0 | Watford |
| November 7 | 2021 | 14:00 | Everton | 0 | 0 | Tottenham H. |
| November 7 | 2021 | 14:00 | Leeds United | 1 | 1 | Leicester |
| November 7 | 2021 | 16:30 | West Ham U. | 3 | 2 | Liverpool |
| November 20 | 2021 | 12:30 | Leicester | 0 | 3 | Chelsea |
| November 20 | 2021 | 15:00 | Aston Villa | 2 | 0 | Brighton |
| November 20 | 2021 | 15:00 | Burnley | 3 | 3 | Crystal Palace |
| November 20 | 2021 | 15:00 | Newcastle | 3 | 3 | Brentford |
| November 20 | 2021 | 15:00 | Norwich City | 2 | 1 | Southampton |
| November 20 | 2021 | 15:00 | Watford | 4 | 1 | Manchester U. |
| November 20 | 2021 | 15:00 | Wolves | 1 | 0 | West Ham U. |
| November 20 | 2021 | 17:30 | Liverpool | 4 | 0 | Arsenal |
| November 21 | 2021 | 14:00 | Manchester C. | 3 | 0 | Everton |
| November 21 | 2021 | 16:30 | Tottenham H. | 2 | 1 | Leeds United |
| November 27 | 2021 | 12:30 | Arsenal | 2 | 0 | Newcastle |
| November 27 | 2021 | 15:00 | Crystal Palace | 1 | 2 | Aston Villa |
| November 27 | 2021 | 15:00 | Liverpool | 4 | 0 | Southampton |
| November 27 | 2021 | 15:00 | Norwich City | 0 | 0 | Wolves |
| November 27 | 2021 | 17:30 | Brighton | 0 | 0 | Leeds United |
| November 28 | 2021 | 14:00 | Brentford | 1 | 0 | Everton |
| November 28 | 2021 | 14:00 | Leicester | 4 | 2 | Watford |
| November 28 | 2021 | 14:00 | Manchester C. | 2 | 1 | West Ham U. |
| November 28 | 2021 | 16:30 | Chelsea | 1 | 1 | Manchester U. |
| November 30 | 2021 | 19:30 | Newcastle | 1 | 1 | Norwich City |
| November 30 | 2021 | 20:15 | Leeds United | 1 | 0 | Crystal Palace |
| December 1 | 2021 | 19:30 | Southampton | 2 | 2 | Leicester |
| December 1 | 2021 | 19:30 | Watford | 1 | 2 | Chelsea |
| December 1 | 2021 | 19:30 | West Ham U. | 1 | 1 | Brighton |
| December 1 | 2021 | 19:30 | Wolves | 0 | 0 | Burnley |
| December 1 | 2021 | 20:15 | Aston Villa | 1 | 2 | Manchester C. |
| December 1 | 2021 | 20:15 | Everton | 1 | 4 | Liverpool |
| December 2 | 2021 | 19:30 | Tottenham H. | 2 | 0 | Brentford |
| December 2 | 2021 | 20:15 | Manchester U. | 3 | 2 | Arsenal |
| December 4 | 2021 | 12:30 | West Ham U. | 3 | 2 | Chelsea |
| December 4 | 2021 | 15:00 | Newcastle | 1 | 0 | Burnley |
| December 4 | 2021 | 15:00 | Southampton | 1 | 1 | Brighton |
| December 4 | 2021 | 15:00 | Wolves | 0 | 1 | Liverpool |
| December 4 | 2021 | 17:30 | Watford | 1 | 3 | Manchester C. |
| December 5 | 2021 | 14:00 | Leeds United | 2 | 2 | Brentford |
| December 5 | 2021 | 14:00 | Manchester U. | 1 | 0 | Crystal Palace |
| December 5 | 2021 | 14:00 | Tottenham H. | 3 | 0 | Norwich City |
| December 5 | 2021 | 16:30 | Aston Villa | 2 | 1 | Leicester |
| December 6 | 2021 | 20:00 | Everton | 2 | 1 | Arsenal |
| December 10 | 2021 | 20:00 | Brentford | 2 | 1 | Watford |
| December 11 | 2021 | 12:30 | Manchester C. | 1 | 0 | Wolves |
| December 11 | 2021 | 15:00 | Arsenal | 3 | 0 | Southampton |
| December 11 | 2021 | 15:00 | Chelsea | 3 | 2 | Leeds United |
| December 11 | 2021 | 15:00 | Liverpool | 1 | 0 | Aston Villa |
| December 11 | 2021 | 17:30 | Norwich City | 0 | 1 | Manchester U. |
| December 12 | 2021 | 14:00 | Burnley | 0 | 0 | West Ham U. |
| December 12 | 2021 | 14:00 | Leicester | 4 | 0 | Newcastle |
| December 12 | 2021 | 16:30 | Crystal Palace | 3 | 1 | Everton |
| December 14 | 2021 | 19:45 | Norwich City | 0 | 2 | Aston Villa |
| December 14 | 2021 | 20:00 | Manchester C. | 7 | 0 | Leeds United |
| December 15 | 2021 | 19:30 | Brighton | 0 | 1 | Wolves |
| December 15 | 2021 | 19:30 | Crystal Palace | 2 | 2 | Southampton |
| December 15 | 2021 | 20:00 | Arsenal | 2 | 0 | West Ham U. |
| December 16 | 2021 | 19:45 | Chelsea | 1 | 1 | Everton |
| December 16 | 2021 | 20:00 | Liverpool | 3 | 1 | Newcastle |
| December 18 | 2021 | 17:30 | Leeds United | 1 | 4 | Arsenal |
| December 19 | 2021 | 14:15 | Newcastle | 0 | 4 | Manchester C. |
| December 19 | 2021 | 14:00 | Wolves | 0 | 0 | Chelsea |
| December 19 | 2021 | 16:30 | Tottenham H. | 2 | 2 | Liverpool |
| December 26 | 2021 | 15:00 | Manchester C. | 6 | 3 | Leicester |
| December 26 | 2021 | 15:00 | Norwich City | 0 | 5 | Arsenal |
| December 26 | 2021 | 15:00 | Tottenham H. | 3 | 0 | Crystal Palace |
| December 26 | 2021 | 15:00 | West Ham U. | 2 | 3 | Southampton |
| December 26 | 2021 | 17:30 | Aston Villa | 1 | 3 | Chelsea |
| December 26 | 2021 | 20:00 | Brighton | 2 | 0 | Brentford |
| December 27 | 2021 | 20:00 | Newcastle | 1 | 1 | Manchester U. |
| December 28 | 2021 | 15:00 | Crystal Palace | 3 | 0 | Norwich City |
| December 28 | 2021 | 15:00 | Southampton | 1 | 1 | Tottenham H. |
| December 28 | 2021 | 15:00 | Watford | 1 | 4 | West Ham U. |
| December 28 | 2021 | 20:00 | Leicester | 1 | 0 | Liverpool |
| December 29 | 2021 | 19:30 | Chelsea | 1 | 1 | Brighton |
| December 29 | 2021 | 20:15 | Brentford | 0 | 1 | Manchester C. |
| December 30 | 2021 | 20:15 | Manchester U. | 3 | 1 | Burnley |
| January 1 | 2022 | 12:30 | Arsenal | 1 | 2 | Manchester C. |
| January 1 | 2022 | 15:00 | Watford | 0 | 1 | Tottenham H. |
| January 1 | 2022 | 17:30 | Crystal Palace | 2 | 3 | West Ham U. |
| January 2 | 2022 | 14:00 | Brentford | 2 | 1 | Aston Villa |
| January 2 | 2022 | 14:00 | Everton | 2 | 3 | Brighton |
| January 2 | 2022 | 14:00 | Leeds United | 3 | 1 | Burnley |
| January 2 | 2022 | 16:30 | Chelsea | 2 | 2 | Liverpool |
| January 3 | 2022 | 17:30 | Manchester U. | 0 | 1 | Wolves |
| January 11 | 2022 | 19:45 | Southampton | 4 | 1 | Brentford |
| January 12 | 2022 | 19:45 | West Ham U. | 2 | 0 | Norwich City |
| January 14 | 2022 | 20:00 | Brighton | 1 | 1 | Crystal Palace |
| January 15 | 2022 | 12:30 | Manchester C. | 1 | 0 | Chelsea |
| January 15 | 2022 | 15:00 | Newcastle | 1 | 1 | Watford |
| January 15 | 2022 | 15:00 | Norwich City | 2 | 1 | Everton |
| January 15 | 2022 | 15:00 | Wolves | 3 | 1 | Southampton |
| January 15 | 2022 | 17:30 | Aston Villa | 2 | 2 | Manchester U. |
| January 16 | 2022 | 14:00 | Liverpool | 3 | 0 | Brentford |
| January 16 | 2022 | 14:00 | West Ham U. | 2 | 3 | Leeds United |
| January 18 | 2022 | 20:00 | Brighton | 1 | 1 | Chelsea |
| January 19 | 2022 | 19:30 | Leicester | 2 | 3 | Tottenham H. |
| January 19 | 2022 | 20:00 | Brentford | 1 | 3 | Manchester U. |
| January 21 | 2022 | 20:00 | Watford | 0 | 3 | Norwich City |
| January 22 | 2022 | 12:30 | Everton | 0 | 1 | Aston Villa |
| January 22 | 2022 | 15:00 | Brentford | 1 | 2 | Wolves |
| January 22 | 2022 | 15:00 | Leeds United | 0 | 1 | Newcastle |
| January 22 | 2022 | 15:00 | Manchester U. | 1 | 0 | West Ham U. |
| January 22 | 2022 | 17:30 | Southampton | 1 | 1 | Manchester C. |
| January 23 | 2022 | 14:00 | Arsenal | 0 | 0 | Burnley |
| January 23 | 2022 | 14:00 | Crystal Palace | 1 | 3 | Liverpool |
| January 23 | 2022 | 14:00 | Leicester | 1 | 1 | Brighton |
| January 23 | 2022 | 16:30 | Chelsea | 2 | 0 | Tottenham H. |
| February 5 | 2022 | 18:00 | Burnley | 0 | 0 | Watford |
| February 8 | 2022 | 19:45 | Newcastle | 3 | 1 | Everton |
| February 8 | 2022 | 19:45 | West Ham U. | 1 | 0 | Watford |
| February 8 | 2022 | 20:00 | Burnley | 1 | 1 | Manchester U. |
| February 9 | 2022 | 19:45 | Manchester C. | 2 | 0 | Brentford |
| February 9 | 2022 | 19:45 | Norwich City | 1 | 1 | Crystal Palace |
| February 9 | 2022 | 19:45 | Tottenham H. | 2 | 3 | Southampton |
| February 9 | 2022 | 20:00 | Aston Villa | 3 | 3 | Leeds United |
| February 10 | 2022 | 19:45 | Liverpool | 2 | 0 | Leicester |
| February 10 | 2022 | 19:45 | Wolves | 0 | 1 | Arsenal |
| February 12 | 2022 | 12:30 | Manchester U. | 1 | 1 | Southampton |
| February 12 | 2022 | 15:00 | Brentford | 0 | 0 | Crystal Palace |
| February 12 | 2022 | 15:00 | Everton | 3 | 0 | Leeds United |
| February 12 | 2022 | 15:00 | Watford | 0 | 2 | Brighton |
| February 12 | 2022 | 17:30 | Norwich City | 0 | 4 | Manchester C. |
| February 13 | 2022 | 14:00 | Burnley | 0 | 1 | Liverpool |
| February 13 | 2022 | 14:00 | Newcastle | 1 | 0 | Aston Villa |
| February 13 | 2022 | 14:00 | Tottenham H. | 0 | 2 | Wolves |
| February 13 | 2022 | 16:30 | Leicester | 2 | 2 | West Ham U. |
| February 15 | 2022 | 20:15 | Manchester U. | 2 | 0 | Brighton |
| February 19 | 2022 | 12:30 | West Ham U. | 1 | 1 | Newcastle |
| February 19 | 2022 | 15:00 | Arsenal | 2 | 1 | Brentford |
| February 19 | 2022 | 15:00 | Aston Villa | 0 | 1 | Watford |
| February 19 | 2022 | 15:00 | Brighton | 0 | 3 | Burnley |
| February 19 | 2022 | 15:00 | Crystal Palace | 0 | 1 | Chelsea |
| February 19 | 2022 | 15:00 | Liverpool | 3 | 1 | Norwich City |
| February 19 | 2022 | 15:00 | Southampton | 2 | 0 | Everton |
| February 19 | 2022 | 17:30 | Manchester C. | 2 | 3 | Tottenham H. |
| February 20 | 2022 | 14:00 | Leeds United | 2 | 4 | Manchester U. |
| February 20 | 2022 | 16:30 | Wolves | 2 | 1 | Leicester |
| February 23 | 2022 | 19:30 | Burnley | 1 | 0 | Tottenham H. |
| February 23 | 2022 | 19:30 | Watford | 1 | 4 | Crystal Palace |
| February 23 | 2022 | 19:45 | Liverpool | 6 | 0 | Leeds United |
| February 24 | 2022 | 19:45 | Arsenal | 2 | 1 | Wolves |
| February 25 | 2022 | 20:00 | Southampton | 2 | 0 | Norwich City |
| February 26 | 2022 | 12:30 | Leeds United | 0 | 4 | Tottenham H. |
| February 26 | 2022 | 15:00 | Brentford | 0 | 2 | Newcastle |
| February 26 | 2022 | 15:00 | Crystal Palace | 1 | 1 | Burnley |
| February 26 | 2022 | 15:00 | Manchester U. | 0 | 0 | Watford |
| February 26 | 2022 | 15:00 | Brighton | 0 | 2 | Aston Villa |
| February 26 | 2022 | 17:30 | Everton | 0 | 1 | Manchester C. |
| February 27 | 2022 | 14:00 | West Ham U. | 1 | 0 | Wolves |
| March 1 | 2022 | 19:45 | Burnley | 0 | 2 | Leicester |
| March 5 | 2022 | 12:30 | Leicester | 1 | 0 | Leeds United |
| March 5 | 2022 | 15:00 | Aston Villa | 4 | 0 | Southampton |
| March 5 | 2022 | 15:00 | Burnley | 0 | 4 | Chelsea |
| March 5 | 2022 | 15:00 | Newcastle | 2 | 1 | Brighton |
| March 5 | 2022 | 15:00 | Norwich City | 1 | 3 | Brentford |
| March 5 | 2022 | 15:00 | Wolves | 0 | 2 | Crystal Palace |
| March 5 | 2022 | 17:30 | Liverpool | 1 | 0 | West Ham U. |
| March 6 | 2022 | 14:00 | Watford | 2 | 3 | Arsenal |
| March 6 | 2022 | 16:30 | Manchester C. | 4 | 1 | Manchester U. |
| March 7 | 2022 | 20:00 | Tottenham H. | 5 | 0 | Everton |
| March 10 | 2022 | 19:30 | Norwich City | 1 | 3 | Chelsea |
| March 10 | 2022 | 19:30 | Southampton | 1 | 2 | Newcastle |
| March 10 | 2022 | 19:30 | Wolves | 4 | 0 | Watford |
| March 10 | 2022 | 19:45 | Leeds United | 0 | 3 | Aston Villa |
| March 12 | 2022 | 12:30 | Brighton | 0 | 2 | Liverpool |
| March 12 | 2022 | 15:00 | Brentford | 2 | 0 | Burnley |
| March 12 | 2022 | 17:30 | Manchester U. | 3 | 2 | Tottenham H. |
| March 13 | 2022 | 14:00 | Chelsea | 1 | 0 | Newcastle |
| March 13 | 2022 | 14:00 | Everton | 0 | 1 | Wolves |
| March 13 | 2022 | 14:00 | Leeds United | 2 | 1 | Norwich City |
| March 13 | 2022 | 14:00 | Southampton | 1 | 2 | Watford |
| March 13 | 2022 | 14:00 | West Ham U. | 2 | 1 | Aston Villa |
| March 13 | 2022 | 16:30 | Arsenal | 2 | 0 | Leicester |
| March 14 | 2022 | 20:00 | Crystal Palace | 0 | 0 | Manchester C. |
| March 16 | 2022 | 19:30 | Brighton | 0 | 2 | Tottenham H. |
| March 16 | 2022 | 20:15 | Arsenal | 0 | 2 | Liverpool |
| March 17 | 2022 | 19:45 | Everton | 1 | 0 | Newcastle |
| March 18 | 2022 | 20:00 | Wolves | 2 | 3 | Leeds United |
| March 19 | 2022 | 12:30 | Aston Villa | 0 | 1 | Arsenal |
| March 20 | 2022 | 14:00 | Leicester | 2 | 1 | Brentford |
| March 20 | 2022 | 16:30 | Tottenham H. | 3 | 1 | West Ham U. |
| April 2 | 2022 | 12:30 | Liverpool | 2 | 0 | Watford |
| April 2 | 2022 | 15:00 | Brighton | 0 | 0 | Norwich City |
| April 2 | 2022 | 15:00 | Burnley | 0 | 2 | Manchester C. |
| April 2 | 2022 | 15:00 | Chelsea | 1 | 4 | Brentford |
| April 2 | 2022 | 15:00 | Leeds United | 1 | 1 | Southampton |
| April 2 | 2022 | 15:00 | Wolves | 2 | 1 | Aston Villa |
| April 2 | 2022 | 17:30 | Manchester U. | 1 | 1 | Leicester |
| April 3 | 2022 | 14:00 | West Ham U. | 2 | 1 | Everton |
| April 3 | 2022 | 16:30 | Tottenham H. | 5 | 1 | Newcastle |
| April 4 | 2022 | 20:00 | Crystal Palace | 3 | 0 | Arsenal |
| April 6 | 2022 | 19:30 | Burnley | 3 | 2 | Everton |
| April 8 | 2022 | 20:00 | Newcastle | 1 | 0 | Wolves |
| April 9 | 2022 | 12:30 | Everton | 1 | 0 | Manchester U. |
| April 9 | 2022 | 15:00 | Arsenal | 1 | 2 | Brighton |
| April 9 | 2022 | 15:00 | Southampton | 0 | 6 | Chelsea |
| April 9 | 2022 | 15:00 | Watford | 0 | 3 | Leeds United |
| April 9 | 2022 | 17:30 | Aston Villa | 0 | 4 | Tottenham H. |
| April 10 | 2022 | 14:00 | Brentford | 2 | 0 | West Ham U. |
| April 10 | 2022 | 14:00 | Leicester | 2 | 1 | Crystal Palace |
| April 10 | 2022 | 14:00 | Norwich City | 2 | 0 | Burnley |
| April 10 | 2022 | 16:30 | Manchester C. | 2 | 2 | Liverpool |
| April 16 | 2022 | 12:30 | Tottenham H. | 0 | 1 | Brighton |
| April 16 | 2022 | 15:00 | Manchester U. | 3 | 2 | Norwich City |
| April 16 | 2022 | 15:00 | Southampton | 1 | 0 | Arsenal |
| April 16 | 2022 | 15:00 | Watford | 1 | 2 | Brentford |
| April 17 | 2022 | 14:15 | Newcastle | 2 | 1 | Leicester |
| April 17 | 2022 | 14:15 | West Ham U. | 1 | 1 | Burnley |
| April 19 | 2022 | 20:00 | Liverpool | 4 | 0 | Manchester U. |
| April 20 | 2022 | 19:45 | Chelsea | 2 | 4 | Arsenal |
| April 20 | 2022 | 19:45 | Everton | 1 | 1 | Leicester |
| April 20 | 2022 | 19:45 | Newcastle | 1 | 0 | Crystal Palace |
| April 20 | 2022 | 20:00 | Manchester C. | 3 | 0 | Brighton |
| April 21 | 2022 | 19:45 | Burnley | 2 | 0 | Southampton |
| April 23 | 2022 | 12:30 | Arsenal | 3 | 1 | Manchester U. |
| April 23 | 2022 | 15:00 | Leicester | 0 | 0 | Aston Villa |
| April 23 | 2022 | 15:00 | Manchester C. | 5 | 1 | Watford |
| April 23 | 2022 | 15:00 | Norwich City | 0 | 3 | Newcastle |
| April 23 | 2022 | 17:30 | Brentford | 0 | 0 | Tottenham H. |
| April 24 | 2022 | 14:00 | Brighton | 2 | 2 | Southampton |
| April 24 | 2022 | 14:00 | Burnley | 1 | 0 | Wolves |
| April 24 | 2022 | 14:00 | Chelsea | 1 | 0 | West Ham U. |
| April 24 | 2022 | 16:30 | Liverpool | 2 | 0 | Everton |
| April 25 | 2022 | 20:00 | Crystal Palace | 0 | 0 | Leeds United |
| April 28 | 2022 | 19:45 | Manchester U. | 1 | 1 | Chelsea |
| April 30 | 2022 | 12:30 | Newcastle | 0 | 1 | Liverpool |
| April 30 | 2022 | 15:00 | Aston Villa | 2 | 0 | Norwich City |
| April 30 | 2022 | 15:00 | Southampton | 1 | 2 | Crystal Palace |
| April 30 | 2022 | 15:00 | Watford | 1 | 2 | Burnley |
| April 30 | 2022 | 15:00 | Wolves | 0 | 3 | Brighton |
| April 30 | 2022 | 17:30 | Leeds United | 0 | 4 | Manchester C. |
| May 1 | 2022 | 14:00 | Everton | 1 | 0 | Chelsea |
| May 1 | 2022 | 14:00 | Tottenham H. | 3 | 1 | Leicester |
| May 1 | 2022 | 16:30 | West Ham U. | 1 | 2 | Arsenal |
| May 2 | 2022 | 20:00 | Manchester U. | 3 | 0 | Brentford |
| May 7 | 2022 | 15:00 | Brentford | 3 | 0 | Southampton |
| May 7 | 2022 | 15:00 | Burnley | 1 | 3 | Aston Villa |
| May 7 | 2022 | 15:00 | Chelsea | 2 | 2 | Wolves |
| May 7 | 2022 | 15:00 | Crystal Palace | 1 | 0 | Watford |
| May 7 | 2022 | 17:30 | Brighton | 4 | 0 | Manchester U. |
| May 7 | 2022 | 19:45 | Liverpool | 1 | 1 | Tottenham H. |
| May 8 | 2022 | 14:00 | Arsenal | 2 | 1 | Leeds United |
| May 8 | 2022 | 14:00 | Leicester | 1 | 2 | Everton |
| May 8 | 2022 | 14:00 | Norwich City | 0 | 4 | West Ham U. |
| May 8 | 2022 | 16:30 | Manchester C. | 5 | 0 | Newcastle |
| May 10 | 2022 | 20:00 | Aston Villa | 1 | 2 | Liverpool |
| May 11 | 2022 | 19:30 | Leeds United | 0 | 3 | Chelsea |
| May 11 | 2022 | 19:45 | Leicester | 3 | 0 | Norwich City |
| May 11 | 2022 | 19:45 | Watford | 0 | 0 | Everton |
| May 11 | 2022 | 20:15 | Wolves | 1 | 5 | Manchester C. |
| May 12 | 2022 | 19:45 | Tottenham H. | 3 | 0 | Arsenal |
| May 15 | 2022 | 12:00 | Tottenham H. | 1 | 0 | Burnley |
| May 15 | 2022 | 14:00 | Aston Villa | 1 | 1 | Crystal Palace |
| May 15 | 2022 | 14:00 | Leeds United | 1 | 1 | Brighton |
| May 15 | 2022 | 14:00 | Watford | 1 | 5 | Leicester |
| May 15 | 2022 | 14:00 | West Ham U. | 2 | 2 | Manchester C. |
| May 15 | 2022 | 14:00 | Wolves | 1 | 1 | Norwich City |
| May 15 | 2022 | 16:30 | Everton | 2 | 3 | Brentford |
| May 16 | 2022 | 20:00 | Newcastle | 2 | 0 | Arsenal |
| May 17 | 2022 | 19:45 | Southampton | 1 | 2 | Liverpool |
| May 19 | 2022 | 19:45 | Everton | 3 | 2 | Crystal Palace |
| May 19 | 2022 | 20:00 | Aston Villa | 1 | 1 | Burnley |
| May 19 | 2022 | 20:00 | Chelsea | 1 | 1 | Leicester |
| May 22 | 2022 | 16:00 | Arsenal | 5 | 1 | Everton |
| May 22 | 2022 | 16:00 | Brentford | 1 | 2 | Leeds United |
| May 22 | 2022 | 16:00 | Brighton | 3 | 1 | West Ham U. |
| May 22 | 2022 | 16:00 | Burnley | 1 | 2 | Newcastle |
| May 22 | 2022 | 16:00 | Chelsea | 2 | 1 | Watford |
| May 22 | 2022 | 16:00 | Crystal Palace | 1 | 0 | Manchester U. |
| May 22 | 2022 | 16:00 | Leicester | 4 | 1 | Southampton |
| May 22 | 2022 | 16:00 | Liverpool | 3 | 1 | Wolves |
| May 22 | 2022 | 16:00 | Manchester C. | 3 | 2 | Aston Villa |
| May 22 | 2022 | 16:00 | Norwich City | 0 | 5 | Tottenham H. |